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No job is more stressful, dangerous or exhilarating than those of the Firefighters, Rescue Squad and Paramedics of Chicago Firehouse 51. These are the courageous men and women who forge headfirst into danger when everyone else is running the other way and whose actions make the difference between life and death. These are their stories.

Dublin, 1868. The Guinness family patriarch is dead, and his four children -- each with dark secrets to hide -- hold the brewery's fate in their hands.

The Ark takes place 100 years in the future when planetary colonization missions have begun as a necessity to help secure the survival of the human race. The first of these missions on a spacecraft known as Ark One encounters a catastrophic event causing massive destruction and loss of life. With more than a year left to go before reaching their target planet, a lack of life-sustaining supplies and loss of leadership, the remaining crew must become the best versions of themselves to stay on course and survive.

The most miserable person on Earth must save the world from happiness.

The doctors of Grey Sloan Memorial Hospital deal with life-or-death consequences on a daily basis -- it's in one another that they find comfort, friendship and, at times, more than friendship. Together they're discovering that neither medicine nor relationships can be defined in black and white. Real life only comes in shades of grey.