The Runaway

Can accidental detective John 'Ludwig' Taylor crack the biggest puzzle of his life - finding his missing brother?

Set in the future, comic book store owner Stuart Bloom is tasked with restoring reality after he breaks a device built by Sheldon, Leonard and Howard, accidentally bringing about a multiverse Armageddon.
Stuart is aided in this quest by his girlfriend Denise, geologist friend Bert, and quantum physicist/all-around pain in the ass Barry Kripke. Along the way, they meet alternate-universe versions of characters we've come to know and love from The Big Bang Theory. As the title implies, things don't go well.

It's Always Sunny in Philadelphia is an American comedy series about four friends in their late 20s with clear sociopathic tendencies who run an unsuccessful Irish bar, "Paddy's Pub," in South Philadelphia. The series deals with a variety of controversial topics, including abortion, gun control, physical disabilities, racism, sexism, religion, the Israeli/Palestinian situation, terrorism, transsexuality, slavery, incest, sexual harassment in education, the homeless, statutory rape, drug addiction, pedophilia, child abuse, mental illness, gay rights and dumpster babies.

Futurama follows pizza guy Philip J. Fry, who reawakens in 31st century New New York after a cryonics lab accident. Now part of the Planet Express delivery crew, Fry travels to the farthest reaches of the universe with his robot buddy Bender and cyclopsian love interest Leela, discovering freaky mutants, intergalactic conspiracies and other strange stuff.

Set 200 years before the events of Game of Thrones, House of the Dragon tells the history of House Targaryen as they fight through a civil war.