Seraph of the End: Vampire Reign - Season 1

A deadly virus sweeps the earth, leaving behind only children and vampires. Yuuichi Nakamura and the other orphans are captured by these vampires and are forced to provide them blood in order to survive. Fed up, they plan on an escape...

Four years later, Yuichiro Hyakuya is a soldier in the Japanese Imperial Demon Army, but he gets suspended for insubordination. As punishment, he attends a school with the order to "make friends.

Yu, Yoichi, and Shinoa go to a restricted area to save someone who was possessed by a demon there.

Mikaela, who was thought to be dead, was actually turned into a vampire by Krul and is working with them. Meanwhile, Yuichiro starts his first day at the Extermination Unit's training school, and already he gets into a fight with one of his classmates...

Eager to obtain the Cursed Gear, Yuichiro tracks down Guren and persuades him to provide him a chance at the Contract Ceremony. Passing Guren's test, Yuichiro, Kimizuki, and Yoichi puts their lives on the line to make a contract with the demon kings.

Kimizuki, Yuichiro, and Yoichi fight against the hallucinations caused by the Black Demons they chose in order to attain their power. They face their tragic memories and fight for control.

Yuichiro, Shinoa, Kimizuki, and Yoichi meet Mitsuba Sangu and form a squad lead by Shinoa. They leave the walls of the Japanese Imperial Demon Army to exterminate vampires. In the meantime, Guren takes a separate route.

With the information obtained from the little girl they saved, Yuichiro and his squad goes to the subway station where the vampires are in order to free the people. However, they quickly learn that everything was a trap from the start...

After saving the captured people from vampires, Yu and his unit reach Shinjuku. However, by the time they reach there, the war had already begun and some vampires had gotten through. To prevent Shijuku from falling, they must fight off the vampires.

Learning that Mitsuba, Kimizuki, and Yoichi are in a pinch, Yu and Shinoa rushes to their rescue. Meanwhile, Guren and his troops fight off the vampire's main forces, but Ferid's strength seems to be out of their league, cornering Guren in a tough spot.

Finally, Mika and Yu reunite, but their circumstances does not allow for much time. Mika tries to "save" Yu from the humans, who have been experimenting on him, but Yu wants to save his squad. Torn between Mika and his squad, something in Yu is awaken...

Trying to figure out what happened to Yu, Shinoa tracks down Guren and asks what he's conspiring to do. However, Guren doesn't answer and keeps it a mystery. When Yu finally wakes up from a seven-day-coma, he explains he doesn't remember what happened.