The Upper Hand (1990-1996)

Set in the future, comic book store owner Stuart Bloom is tasked with restoring reality after he breaks a device built by Sheldon, Leonard and Howard, accidentally bringing about a multiverse Armageddon.
Stuart is aided in this quest by his girlfriend Denise, geologist friend Bert, and quantum physicist/all-around pain in the ass Barry Kripke. Along the way, they meet alternate-universe versions of characters we've come to know and love from The Big Bang Theory. As the title implies, things don't go well.

Tulsa King follows New York mafia capo Dwight "The General" Manfredi, just after he is released from prison after 25 years and unceremoniously exiled by his boss to set up shop in Tulsa, Oklahoma. Realizing that his mob family may not have his best interests in mind, Dwight slowly builds a "crew" from a group of unlikely characters, to help him establish a new criminal empire in a place that, to him, might as well be another planet. 

Doc centers on the hard-charging, brilliant Dr. Amy Larsen, Chief of Internal and Family Medicine at Westside Hospital in Minneapolis. After a brain injury erases the last eight years of her life, Amy must navigate an unfamiliar world where she has no recollection of patients she's treated, colleagues she's crossed, the soulmate she divorced, the man she now loves and the tragedy that caused her to push everyone away. She can rely only on her estranged 17-year-old daughter, whom she remembers as a 9-year-old, and a handful of devoted friends, as she struggles to continue practicing medicine, despite having lost nearly a decade of knowledge and experience.

In Boston Blue, NYPD Detective Danny Reagan takes a position with Boston PD. Once in Boston, he is paired with Detective Lena Silver, the eldest daughter of a prominent law enforcement family.

Hailed as one of the best sci-fi novels of the decade, Dark Matter is a story about the road not taken. The series follows Jason Dessen, a physicist, professor, and family man who – one night while walking home on the streets of Chicago – is abducted into an alternate version of his life. Wonder quickly turns to nightmare when he tries to return to his reality amid the multiverse of lives he could have lived. In this labyrinth of mind-bending realities, he embarks on a harrowing journey to get back to his true family and save them from the most terrifying, unbeatable foe imaginable: himself.